Magnetic targeting of nanoparticles across the intact blood–brain barrier
نویسندگان
چکیده
منابع مشابه
Magnetic targeting of nanoparticles across the intact blood-brain barrier.
Delivery of therapeutic or diagnostic agents across an intact blood-brain barrier (BBB) remains a major challenge. Here we demonstrate in a mouse model that magnetic nanoparticles (MNPs) can cross the normal BBB when subjected to an external magnetic field. Following a systemic administration, an applied external magnetic field mediates the ability of MNPs to permeate the BBB and accumulate in ...
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ژورنال
عنوان ژورنال: Journal of Controlled Release
سال: 2012
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2012.09.021